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Best Glutathione Supplement
Our Top Picks of the Best Glutathione Supplement
If you’re searching for the Best Glutathione Supplement, this guide makes it simple. Glutathione is widely known as the body’s “master antioxidant,” supporting immune strength, detoxification, energy, and healthy aging—but not all supplements are created equal. Below, we break down the top glutathione formulas based on purity, bioavailability, research, and real-world results so you can confidently choose the Best Glutathione Supplement for your health goals.
Our Top Picks is Immunocal by Immunotec
#1 Immunocal
Overall Rating (4.6)
Immunocal is our top pick because it’s one of the few glutathione-support supplements backed by decades of research, global patents, and clinical testing. Its unique whey protein isolate formula delivers bonded cysteine, the key building block your body needs to produce glutathione naturally.
- Patented bonded cysteine formula
- Backed by 45+ years of research
- Clean, high-purity whey protein isolate
Our #2 Picks is Glutathione by NOW Foods Supplements
#2 Glutathione 500 mg
Overall Rating (4.6)
NOW Foods Glutathione Reduced earns the #2 position for its affordability, simplicity, and long-standing trust in the supplement industry. Each capsule contains 500 mg of reduced glutathione, along with added milk thistle and alpha-lipoic acid for antioxidant support. While it doesn’t offer the bioavailability of liposomal or precursor formulas, it’s one of the best budget-friendly options for users seeking basic glutathione support from a highly reputable brand.
- 500 mg reduced glutathione per capsule
- Added ALA and milk thistle for antioxidant synergy
- Non-GMO and third-party tested
Our #3 Pick is Liposomal Glutathione by Pure Encapsulations
#3 Liposomal Glutathione
Overall Rating (4.5)
Pure Encapsulations Liposomal Glutathione ranks at #5 for its ultra-clean, hypoallergenic formula and practitioner-trusted reputation. This product uses a high-quality liposomal delivery method to improve absorption while maintaining extremely pure ingredients. It’s ideal for individuals with sensitivities, or anyone seeking a premium liposomal glutathione supplement from a clinical-grade brand.
- High-purity liposomal glutathione formula
- Hypoallergenic and free from common allergens
- Backed by a respected practitioner-focused brand
Our #4 Pick is Liposomal Glutathione by LivOn Labs
#4 Liposomal Glutathione (Lypo-GSH)
Overall Rating (4.4)
LivOn Labs Liposomal Glutathione earns our #2 spot thanks to its highly bioavailable liposomal delivery system, allowing glutathione to be absorbed more efficiently than standard capsules or powders. Each packet contains 450mg of reduced glutathione wrapped in phospholipids to help protect it from stomach acid and improve cellular uptake. It’s a strong option for users who want a direct glutathione supplement with fast absorption and a clean ingredient profile.
- True liposomal delivery for enhanced absorption
- 450mg reduced glutathione per packet
- Non-GMO, sugar-free, and allergen-friendly
Our #5 Pick is Liposomal Glutathione by Rho Nutrition
#5 Liposomal Glutathione
Overall Rating (4.3)
Rho Nutrition Liposomal Glutathione earns our #2 spot for its clean formulation, strong customer reviews, and highly absorbable liposomal delivery system. Each serving contains reduced glutathione wrapped in phospholipids designed to help the body absorb it more efficiently than standard capsules. It’s a great option for people seeking a direct glutathione supplement with excellent value and solid real-world results.
- Advanced liposomal delivery for improved absorption
- 500 mg reduced glutathione per serving
- Clean formula with no unnecessary fillers
